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Overview

Projects
January 2023 - Present
 Research project entitled: Development and optimization of an extraction and purification method for 6-hydroxy-L-nicotine from the growth medium of Paenarthrobacter nicotinovorans, Code  GI-UAIC-2022-08 (Total amount 10 000 euros)
Publications
2024
  1. Brinza I, Boiangiu RS, Mihasan M, Gorgan DL, Stache AB, Abd-Alkhalek A, El-Nashar H, Ayoub I, Mostafa N, Eldahshan O, Singab AN, Hritcu L, 2024 – Rhoifolin, baicalein 5,6-dimethyl ether and agathisflavone prevent amnesia induced in scopolamine zebrafish (Danio rerio) model by increasing the mRNA expression of bdnf, npy, egr-1, nfr2α, and creb1 genes. European Journal of Pharmacology, 984(2024), 177013, 1-29;
  2. Bouabdallah S, Ibrahim MH, Brinza I, Boiangiu RS, Honceriu I, Amin A, Ben-Attia M, Hritcu L, 2024 – Anxiolytic and Antidepressant Effects of Tribulus terrestris Ethanolic Extract in Scopolamine-Induced Amnesia in Zebrafish: Supported by Molecular Docking Investigation Targeting Monoamine Oxidase A. Pharmaceuticals, 17(9), 1208;
  3. Brinza I, Boiangiu RS, Honceriu I, Abd-Alkhalek AM, Eldahshan OA, Dumitru G, Hritcu L, Todirascu-Ciornea E, 2024 – Investigating the Potential of Essential Oils from Citrus reticulata Leaves in Mitigating Memory Decline and Oxidative Stress in the Scopolamine-Treated Zebrafish Model. Plants, 13(12), 1648.
  4. Bouabdallah S, Brinza I, Boiangiu RS, Ibrahim MH, Honceriu I, Al-Maktoum A, Cioanca O, Hancianu M, Amin A, Ben-Attia M, Hritcu L. 2024 – The Effect of a Tribulus-Based Formulation in Alleviating Cholinergic System Impairment and Scopolamine-Induced Memory Loss in Zebrafish (Danio rerio): Insights from Molecular Docking and In Vitro/In Vivo Approaches. Pharmaceuticals, 17(2), 200.
  5. Boiangiu RS, Brinza I, Honceriu I, Mihasan M, Hritcu L; 2024 – Insights into Pharmacological Activities of Nicotine and 6-Hydroxy-L-nicotine, a Bacterial Nicotine Derivative: A Systematic Review. Biomolecules, 14(1), 23;
2023; 2022; 2021; 2020; 2019; 2018

Books and book chapters
Hritcu L, Boiangiu RS, Edmond MP, Eldahshan OA (2023). Baicalin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology. In: Xiao, J. (eds) Handbook of Dietary Flavonoids. Springer, Cham. https://doi.org/10.1007/978-3-030-94753-8_4-1;
Abstract publications
2024
  1. Boiangiu RS, Mihasan M – Impact of 3D-printed molecular models on teaching – a compensatory research study. FEBS Open Bio, 14: S2, pp. 511, P-E-01-03;
  2. Hritcu L, Boiangiu RS, Honceriu I, Brinza I, Mihasan M – 6-Hydroxy-L-nicotine alleviates cognitive impairments in 5XFAD transgenic mice. FEBS Open Bio, 14: S2, pp. 402-403, P-32-057;
  3. Boiangiu RS, Brinza I, Orhan IE, Hritcu L – The impact of Myrtus communis essential oil on cognition, anxiety and oxidative stress in a zebrafish (Danio rerio) model of Alzheimer’s disease. FEBS Open Bio, 14: S2, pp. 366, P-30-048;
2023; 2022; 2021; 2020; 2019; 2015-2018

Conferences
2024
  1. Boiangiu RS, Brinza I, Orhan IE, Hritcu L – Promnesic, anxiolytic and antioxidant effects of Myrtus communis essential oil in a zebrafish (Danio rerio) model of dementia – TBS International Biochemistry Congress 2024 – 35th National Biochemistry Congress, Antalya, Turkyie, 27 October - 1 November 2024;
  2. Băsu LI, Boiangiu RS – In silico molecular docking of nicotine and nicotinic derivatives to β-amyloid peptide – TBS International Biochemistry Congress 2024 – 35th National Biochemistry Congress, Antalya, Turkyie, 27 October - 1 November 2024;
  3. Boiangiu RS, Brinza I, Orhan IE, Hritcu L – Promnesic, anxiolytic and antioxidant effects of Myrtus communis essential oil in a zebrafish (Danio rerio) model of dementia– the VIIth National Conference with International Participation: Natural sciences in the dialogue of generations, Chisinau, Republic of Moldova, 11-12 September, 2024;
  4. Boiangiu RS, Brinza I, Orhan IE, Hritcu L – Beneficial effects of Myrtus communis essential oil on memory, anxiety and oxidative stress in a zebrafish model of dementia – 8th International Symposium on Phytochemicals in Medicine and Food, Shenyang, China, 2-7 August 2024.
  5. Boiangiu RS, Brinza I, Orhan IE, Hritcu L – The impact of Myrtus communis essential oil on cognition, anxiety and oxidative stress in a zebrafish (Danio rerio) model of Alzheimer’s disease – The 48th FEBS Congress: Mining biochemistry for human health and well-being, Milan, Italy, 29 June – 3 July 2024;
2023; 2022; 2021; 2020; 2019; 2014-2018;

Awards & Travel Grants
FEBS-IUBMB-ENABLE European travel grant for attending the 2nd International Molecular Biosciences PhD & Postdoc Conference (FEBS-IUBMB-ENABLE 2023)
The best poster presentation award on the 5th International Conference on Natural Products Utilization: from Plants to Pharmacy Shelf (ICNPU 2023)
Dra. Mariola Macias Award (2nd place) offered by the Phytochemical Society of Europe (PSE)
2 Excellence Awards offered by Alexandru Ioan Cuza University of Iasi
YSF grant for attending the 20th FEBS Young Scientists’ Forum (YSF) and the 45th FEBS Congress (Virtual, 2021);
FENS-IBRO/PERC Grant for attending FENS Forum 2020;
2 FEBS bursaries for attending the 43th FEBS Congress (Prague, Czech Republic, 2018) and the  IUBMB-FEBS-PABMB Congress (Lisbon, Portugal, 2022);